Featured patents

Anti-Axl Antibodies and Methods of Use
US 08853369 B2, Oct. 7, 2014, Binds antigen characterized by name or molecular weight, Lin Pei et al. / Genentech, Inc. (South San Francisco, US)
An isolated antibody that binds to human Axl, wherein the antibody binds human…

Anti-Ron Antibodies
US 08829164 B2, Sept. 9, 2014, Chimeric, mutated, or recombined hybrid, Sylvie Vincent et al. / AVEO Pharmaceuticals, Inc. (Cambridge, US)
An isolated antibody that binds human RON (Recepteur d'Origine Natais),…

Optimized Fc Variants and Methods for Their Generation
US 08809503 B2, Aug. 19, 2014, Immunoglobulin, antibody, or fragment thereof, other than immunoglobulin antibody, or fragment thereof that is conjugated or adsorbed, John Desjarlais et al. / Xencor, Inc. (Monrovia, US)
A variant Fc region of a human parent IgG1 Fc region, wherein said variant…

Purification of Low Isoelectric Point Isoforms of Darbepoietin
US 08779110 B2, July 15, 2014, Immunological separation or affinity chromatography, Darshan Koticha et al. / Dr. Reddy's Laboratories Limited (Hyderabad, IN)
A process for the isolation of isoforms of darbepoetin of isoelectric point (pI)…

Human Frizzled (FZD) Receptor Polypeptides and Methods of Use Thereof for Treating Cancer and Inhibiting Growth of Tumor Cells
US 08765913 B2, July 1, 2014, Proteins, i.e., More Than 100 Amino Acid Residues, Timothy Hoey et al. / OncoMed Pharmaceuticals, Inc. (Redwood City, US)
A polypeptide consisting of (a) a fragment of an extracellular domain of a human…

Refolding Transforming Growth Factor Beta Family Proteins
US 08722862 B2, May 13, 2014, Physical treatment, Anthony Rossomando et al. / Biogen Idec MA Inc. (Cambridge, US)
A composition comprising an amount of a refolding buffer effective to,…

Cancer Related Isoforms of Components of Transcription Factor Complexes as Biomarkers and Drug Targets
US 08664359 B2, March 4, 2014, Proteins, i.e., More Than 100 Amino Acid Residues, Anna Kazantseva et al. / OncoTx, Inc. (Los Angeles, US)
An isolated or recombinant cancer-specific polypeptide comprising a polypetide…

Pertussis Antibodies and Uses Thereof
US 08653243 B2, Feb. 18, 2014, Chimeric, mutated, or recombined hybrid, Jamie Sutherland et al. / Board of Regents, The University of Texas System (Austin, US)
A humanized antibody capable of binding a pertussis toxin protein, wherein…

Modified Clostridial Toxins With Enhanced Targeting Capabilities for Endogenous Clostridial Toxin Receptor Systems
US 08623999 B2, Jan. 7, 2014, Proteins, i.e., More Than 100 Amino Acid Residues, Joseph Francis et al. / Allergan, Inc. (Irvine, US)
A modified di-chain Clostridial toxin comprising:…

Antigen Associated With the Neovasculature of Tumour Metastases
US 08481684 B2, July 9, 2013, Immunoglobulin, antibody, or fragment thereof, other than immunoglobulin antibody, or fragment thereof that is conjugated or adsorbed, Jascha-Nikolai Rybak et al. / Philogen S.p.A. (Siena, IT)
An isolated antibody or antigen binding fragment thereof, which binds the Extra…

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