Featured patents

BAB Triblock Polymers Having Improved Release Characteristics
US 08753621 B2, June 17, 2014, Ramesh C. Rathi et al. / Protherics Salt Lake City, Inc. (Salt Lake City, US)
A BAB-block copolymer comprising:…

Compositions Comprising Apolipoprotein a Polypeptide and Interleukin 15, and Methods of Treatment Using the Same
US 08771664 B2, July 8, 2014, Maria del Carmen Ochoa Nieto et al. / Fundacion para la Investigacion Medica Aplicada (Pamplona (Navarra), ES
A composition comprising, separately or in the form of a single fusion molecule,…

Derivatised Proline Containing Peptide Compounds as Protease Inhibitors
US 08512690 B2, Aug. 20, 2013, Pascal Rigollier et al. / Novartis AG (Basel, CH)
A compound or a pharmaceutically acceptable salt thereof selected from the group…

Expansion of Haemopoietic Precursors
US 08828375 B2, Sept. 9, 2014, Michael David Schuster et al. / Mesoblast, Inc. (New York, US)
A method of transplanting haematopoietic precursor cells into a subject in need…

Granulysin in Immunotherapy
US 08815229 B2, Aug. 26, 2014, Carol Clayberger et al. / The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, US)
A method of stimulating production of a monocyte-derived dendritic cell,…

Hepatitis C Virus Inhibitors
US 08846023 B2, Sept. 30, 2014, Fukang Yang et al. / Bristol-Myers Squibb Company (Princeton, US)
A compound selected…

Hepatitis C Virus Inhibitors
US 08642025 B2, Feb. 4, 2014, Jeffrey Lee Romine et al. / Bristol-Myers Squibb Company (Princeton, US)
A compound of Formula (I)…

Hepatitis C Virus Inhibitors
US 08574563 B2, Nov. 5, 2013, Andrew C. Good et al. / Bristol-Myers Squibb Company (Princeton, US)
A compound of Formula (I)…

Heterocyclic Antiviral Compounds
US 08734777 B2, May 27, 2014, Francisco Xavier Talamas et al. / Roche Palo Alto LLC (South San Francisco, US)
A compound selected from the group consisting of:…

Human IL-23 Antigen Binding Proteins
US 08722033 B2, May 13, 2014, Heather Cerne et al. / Amgen Inc. (Thousand Oaks, US)
An isolated antigen binding protein that binds IL-23, comprising at least one…

IL-11 Muteins
US 08540977 B2, Sept. 24, 2013, Manuel Baca / CSL Limited (Parkville, Victoria, AU)
A human IL-11 mutein comprising:…

IL-1F5 Polypeptides
US 08481021 B2, July 9, 2013, Christopher Gabel et al. / Amgen Inc. (Thousand Oaks, US)
An isolated IL-1F5 polypeptide that antagonizes signal transduction through…

IL-1F8 Polypeptides
US 08871192 B2, Oct. 28, 2014, Blair R. Renshaw et al. / Amgen Inc. (Thousand Oaks, US)
An isolated IL-1F8 polypeptide that agonizes signal transduction/activation…

IL-21 Variants
US 08475784 B2, July 2, 2013, Kent Bondensgaard et al. / Novo Nordisk A/S (Bagsvaerd, DK)
An isolated variant IL-21 peptide comprising an amino acid sequence, which varies…

Inflammation-Inhibitory Serum Factors and Uses Thereof
US 08821851 B2, Sept. 2, 2014, Jean-Marc Cavaillon et al. / The General Hospital Corporation (Boston, US)
A method of reducing an inflammatory response or reducing the risk of developing…

Interleukin-1 Muteins Linked to Virus-Like Particles to Treat IL-1 Associated Diseases
US 08449874 B2, May 28, 2013, Martin F. Bachmann et al. / Cytos Biotechnology AG (Zurich-Schlieren, CH)
A composition comprising:…

Interleukin-10 Peptides and Antibodies Thereof for Inhibiting Adverse Effects of Protozoan Infection
US 08652457 B2, Feb. 18, 2014, Mark Eric Cook et al. / Wisconsin Alumni Research Foundation (Madison, US)
An isolated interleukin-10 peptide consisting of an amino acid sequence selected…

Method for Treating Cervical Cancer
US 08486382 B2, July 16, 2013, Patricia A. McKernan et al. / ZymoGenetics, Inc. (Seattle, US)
A method for inhibiting the proliferation of a human papillomavirus…

Method of Treating Hair Loss With Compositions Containing Interleukin-1
US 08603456 B2, Dec. 10, 2013, Tatiana Vyacheslavovna Popkova et al. / United Technologies UT AG (Zurich, CH)
A method for treating hair loss, comprising the steps of:…

Method of Treatment of Gastrointestinal Disorders With IL-10
US 08765115 B2, July 1, 2014, Fumio Takaiwa et al. / National Institute of Agrobiological Scienses (Ibaraki, JP)
A treatment method for an inflammatory gastrointestinal disorder, wherein…

Methods and Compositions for Contributing to the Treatment of Cancers
US 08642026 B2, Feb. 4, 2014, Luigi Lenaz et al. / Spectrum Pharmaceuticals, Inc. (Irvine, US)
A method of selectively increasing delivery of a chemotherapeutic agent…

Methods for Treating Acute Myeloid Leukemia With Diphtheria Toxin-Interleukin-3 Conjugates
US 08470307 B2, June 25, 2013, Arthur E. Frankel / Scott & White Memorial Hospital (Temple, US)
A method for inhibiting acute myeloid leukemia (AML) cells in a human diagnosed…

Modulation of Regulatory T Cells by Human IL-18
US 08679471 B2, March 25, 2014, Carl H. June et al. / The Trustees of the Univesity of Pennsylvania (Philadelphia, US)
A method of treatment comprising:…

Mutants of IL-29
US 08734776 B2, May 27, 2014, Dennis L. Dong et al. / ZymoGenetics, Inc. (Seattle, US)
An isolated polypeptide comprising an amino acid sequence having at least 97%…

Pegylated Interleukin-10
US 08697045 B2, April 15, 2014, Seoju Lee et al. / Merck Sharp & Dohme Corporation (Rahway, US)
A mono-pegylated interleukin-10 (mono-PEG-IL-10) comprising one or more…

Peptidomimetic Protease Inhibitors
US 08529882 B2, Sept. 10, 2013, Xicheng David Sun et al. / Vertex Pharmaceuticals Incorporated (Cambridge, US)
A method of treating a hepatitis C virus infection in a patient, comprising…

Peptidomimetic Sulfamide Compounds and Antiviral Uses Thereof
US 08840878 B2, Sept. 23, 2014, Oliver Simic et al. / Novartis AG (Basel, CH)
A compound of Formula (III):…

Peptidomimetic Sulfamide Compounds and Antiviral Uses Thereof
US 08613914 B2, Dec. 24, 2013, Prakash Raman et al. / Novartis AG (Basel, CH)
A method of treating an HCV-associated disorder, comprising:…

Pre-Ligand Assembly Domain of the IL-17 Receptor
US 08460647 B2, June 11, 2013, Sarah L. Gaffen et al. / Amgen Inc. (Thousand Oaks, US)
An isolated polypeptide consisting of the amino acid sequence of SEQ ID NO[s]: 4…

Programming of Cells for Tolerogenic Therapies
US 08728456 B2, May 20, 2014, Toshihisa Kawai et al. / President and Fellows of Harvard College (Cambridge, US)
A method of reducing the severity of an autoimmune disorder, comprising…

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